ABSTRACT
Background: Diabetic retinopathy is one of the leading causes of blindness in the world. Hypomagnesaemia has been reported to occur at an increased frequency among patients with type 2 diabetes mellitus (DM) with retinopathy compared with their counterparts without diabetic retinopathy. The study was done with aimed whether there is any correlation between serum magnesium concentration and diabetic retinopathy in a rural population. Aim: This study was carried out to find the correlation between serum magnesium levels in diabetic patients with retinopathy. Methods: 100 type 2 DM patients admitted in NIMS Medical Collage Hospital, Jaipur over the period of 8 months between 1st December 2014 to 31th July 2015, were selected for this study. Detailed history, general physical examination, systemic examination, and various investigations like fasting blood sugar (FBS), post prandial blood sugar after 2 hrs (PP2BS), glycosylated hemoglobin (HbA1C), Blood urea, serum creatinine and urine examination were carried out. Serum magnesium was estimated by Calmagite dye method. Retinopathy was assessed by direct opthalmoscopy. Results: Prevalence of hypomagnesaemia in type 2 diabetic was 30% hypomagnesaemia was significantly higher in diabetic with retinopathy compared to diabetic without retinopathy. Serum magnesium level is in uncontrolled DM when compare with control DM. No significant associations existed between serum magnesium concentrations and other factors like age, sex, durations of diabetes, mode of treatment. Conclusion: Prevalence of hypomagnesaemia in type 2 diabetics is 30%, And especially more significant in diabetes with retinopathy when comparison to diabetes without retinopathy.